There are many ways to get to Kinderdijk by motorway. If you're coming from Rotterdam, drive south along motorway A16 in the direction to Dordrecht. At the junction, get onto the A15 that goes in eastward direction to Gorinchem. Get off at exit 22 and follow the signs to Kinderdijk.
If you're coming from Amsterdam or Utrecht, drive south along motorway A2. At the junction Everdingen, get onto motorway A27 that goes to Gorinchem in southwestern direction. At the junction Gorinchem, get onto motorway A15 that goes to Rotterdam in westwards direction. Get off at exit 22 and follow the signs to Kinderdijk. The ride is about 100 km from Amsterdam.