The major centers Tarquinia, Capalbio, Orbetello, Grosseto, Cecina on the coast between Rome and Pisa are well connected through railway and motorway "via Aurelia". Trains stops in minor centers with lesser frequency.

The nearest airports are located in Rome about 70 km from Tarquinia , Pisa about 60 km from Cecina and Florence about 80 km from Grosseto.

To reach minor centers, especially the ones located in the internal parts of Maremma, a car is required. Also by car, these centers are linked by tortuous roads, climbing up and down from the hills.