By train
From elsewhere in the Netherlands, Enschede is easily accessible by train from all major Dutch cities, and can be reached from smaller cities with at most one or two transfers. The journey time from Amsterdam is approximately two hours. An excellent train only travel planner is available at Nationale Spoorwegen (http://ns.nl/). If you need to use a connecting bus or ferry from within the Netherlands, use 9292OV (http://9292ov.nl).
From Germany, direct trains ending in Enschede are available from Gronau, Dortmund, and Münster. To reach Enschede from Berlin, a stopover is available in Hengelo a small city about 10 minutes by train from Enschede. Further guidance is available at Die Bahn (http://www.db.de).
By car
There is a large parking garage underneath the marketsquare in the center of the city, the H.J. van Heekplein , which provides approximately 2000 parking spaces for visitors arriving by car.
Alternatively, there is a cheaper park and ride solution available at the recently 2008 expanded P+R Zuiderval . Frequent busses travel from here direct to the city center approximately 5 minutes by bus. This is especially useful if you are arriving in Enschede via the highway, as the lot is just off the highway exit.