Laufenburg has two railway stations on opposite sides of the Rhine, one belonging to DB German railways and one to SBB Swiss Railways. The Swiss station has hourly direct trains from Basel Swiss Station. The German station has hourly direct trains from Basel German Station and from Waldshut change here for Schaffhausen and Zürich. If you arrive from Basel the Swiss train is usually somewhat cheaper but the view from the German side makes it the preferable choice. Post buses also connect Laufenburg with Aarau, Brugg and Frick. The roads leading to Laufenburg also go along the banks of the Rhine. Nearby airports are EuroAirport Basel and Zürich.
