By plane
Hagerstown is home to the one small regional airport with flights from BWI, but a car is a far, far more common mode of transport, especially as you will need one once you arrive!
By train
Amtrak has daily trains to Hagerstown and Cumberland from Washington, D.C.The MARC Brunswick Line (http://mta.maryland.gov/s...) from Washington, D.C. is nice and cheap, but will only take you as far as Brunswick in Washington County. It only runs on the weekdays, catering to commuters.
By car
To get around much anywhere in Western Maryland, you will need a car, and a car is a fine way to arrive. I-68 is the main east-west highway, running from Hagerstown and the junction with I-70 in the east which is the highway in from Baltimore and Washington, D.C. and from Morgantown, West Virginia, in the west.North-south routes are mostly smaller, although from Hagerstown, you can take I-70 to Pittsburgh or I-81 towards Harrisburg. US-220 connects Cumberland with I-70 in the north towards Pittsburgh, and also leads south through some incredibly beautiful and remote landscapes in West Virginia.