Apply common sense and take precautions that apply elsewhere. All tourists should be careful when selecting a travel guide and never accept medication from unverifiable sources. Women tourists should be cautious when traveling alone. At night try to use "radio taxis" as fake cabs are common and robbings and even rapes do occur. It is a good idea to register with the consulate of your country of residence upon entry into the country. And it is also helpful learn at least basic Spanish to keep yourself a little safe.
Some parts of Bolivia like La Paz 3650, PotosÃ 4010, Oruro 3950 and the Lake Titicaca region are high altitude, so adequate precautions against "sorojchi" altitude sickness should be taken.
At local pharmacies they sell sorojchi pills, that are supposed to help with altitude problems. It has painkillers as well as natural herbs to help cope with the symptoms of "sorojchi". In many parts of the Altiplano you can purchase coca leaves, which are reputed to be useful against soroche. Coca tea "mate de coca" is available in tea bags in many markets.
However, severe cases of high altitude disease can be treated at the High Altitude Pathology Institute at Clinica IPPA (http://altitudeclinic.com). This Clinic has the most advanced technology including a hyperoxic/hypoxic adaptation chamber. In addition, the sun's ultraviolet rays are much stronger -- up to 20 times -- than at sea level. A sun hat, sunglasses, and skin protection sunblock or long sleeves are advised.
Yellow fevervaccination is recommended for those who plan on spending time in the Bolivian Amazon. It must be taken 10 days prior to the personâs arrival into the country if the visitor plans to visit rural areas.
Malariaprophylaxis is recommended if the visitor plans to visit tropical-rural areas.
As a preventive measure, taking the following vaccines is recommended: Hepatitis A, Hepatitis B and Tetanus, Diphtheria and Measles Booster-Vaccines.
Bolivia has 37 official languages -of which Spanish often called Castellano, Quechua, and Aymara are the main ones. In rural areas, many people do not speak Spanish. Nevertheless, you should be able to get by with some basic Castellano. Bolivia is one of the best places in which to learn or practice your Spanish because of their very clean, deliberate accent. There are many options for studying Spanish in Bolivia, and they are usually very good often, the program includes a very good homestay component.