To get to San Buenaventura across the RÃo Beni take one of the water taxis at Calle Santa Cruz for 1 Boliviano.
By plane
A tarmac strip outside town is the main airport. In case it's flooded companies use the landing strip at Reyes, about 45 mins. away. There are daily connections to La Paz, but cancellations are common, especially in the rainy season.
TAM
Santa Cruz s/n, has around two flights weekly to La Paz for Bs465. TAM likes the mastercard and Visa logos painted on their office, but only accepts cash or travellers checks July 2009 they report to accept credit cards.Amaszonas
(http://www.amaszonas.com/), Santa Cruz s/n, tel/fax 38922472, is slightly pricier with Bs525, but has several flights daily. Visa and mastercard are accepted, that is, if their reader works.Their website doesn't seem to work correctly April 2012, you can book an fully booked flight. Better to go to the office or a travel agency.Don't forget to reconfirm your flight on the day before, and also on the day you fly.
If you're going east or north from Rurrenabaque there's a flight with TAM from Reyes to the cities of San Borja, Trinidad, Riberalta and Guayará-Mirim on the border with Brazil.
By bus
There are daily buses to and from La Paz. The journey takes 20 hours. There are generally more people on the bus than seats and there isn't much space to put your legs. You can break the trip in Coroico, which is only 17 hours away. On a part of the road from La Paz to Coroico a new highway has been opened at the end of 2006, and the old 'death road' is now only for bikers. The new road only avoids a part of the 'death road' or Yungas Road. From Coroico Yolosita to Caranavi is another two to three hours on the death road, with the roadside canyon just a few hundred feet deep instead of a few hundred metres.
There are also daily buses to Riberalta and Guayará-Mirim. Inquire about departure times at the bus terminal; they vary wildly. During the rainy season, this road is virtually impassable, and trips may take up to six days. When the road's in good condition, Rurrenabaque-Riberalta should take about 20 hours, and Guayará another four.
There are two offices on Avaroa offering jeep services to nearby towns and even La Paz US$25 and only 12 hours. Also you can see all the information about bus travel in (http://www.boliviabus.com) a travel guide is very useful for travel in Bolivia.